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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5f724478cfc260a0b3716b52afc4ebda574281967cdf6f330dfcc00be13ba5' 
  AND token = 'QxWNGBpm4+fhaZkZalY6H53vPZZH1VTePDj1Qr3OfxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}