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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3ab6da68997965096a3ae313b1a2950241f8a87e33e2fcc49f4f9a49e74afb' 
  AND token = 'LU8K6dKDgob0CC3CdjL0oEpNaKhwJMFZim2hghuHTWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}