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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed1d4a267daa37d4506c8dc8e92c20539a9fe80c1bdf4376401b1eda33a0d63' 
  AND token = '5FaDWq4TZzl2YfBmJgJqBXknUyHcggqxm9ErtoVxWhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}