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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9cacc6da3f1411e722cc5e1b4acf24c732d81f39c53d4500500a7227451772' 
  AND token = 'Wbl7u5t8EtXhfsYHrBhLbnkUMQ1bvXNMEV/IueArFJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}