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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881a1e2fd49616e7d0e4a9ea68e490c7732bb5b7135aa10e43c115eb4b0c8ca2' 
  AND token = 'Po8E2w7hiGUuexFbKyqLrQ4hV2ZJPeq0OUNTgyINzC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}