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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492f006b6c2e9cb7481b5ac70dd2599f2fbe0d44085ac69525b6d17ea576f85c' 
  AND token = 'V+GWSpFhcEZY4809AqSY8U8bgtDpVNCRgMgD9LZYTis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}