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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1225e330912312c0ac309b8773f9837c8e7d86781c46d41b0821b8359c75e3d8' 
  AND token = 'jJW9zmDIIqpQXntQsUUYAB6qZ3n4rDoYZJW81f0Z36U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}