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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d3fff76b76aac9e349417f149ea5f839606b3ef35144f1264b12ebf44d8df3' 
  AND token = 'aNS+3bjdOneIgkDvLk6G5d58u10EjT683eGqq27L8g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}