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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b73caf57776cc0bb5fb01a2808825829e5fa3c3b2d4b3a5d77cbd69585794201' 
  AND token = 'zkgUHBQCG3nkYBDv6rvJDDOCR3QNnnUNtPNTTov/3IE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}