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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46fa602d6c1354a4b306abbed4db2de144a8553d817f97cce64ffadede56ca9' 
  AND token = 'rGucTh+SAKqnoNxZ06Q0P4Ylq3DzBLGRP063ox7AwM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}