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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aeb973603393ac16432d83860af31e9622e8dcff382ccf60f7a3016b6ec2868' 
  AND token = '+cNVDehl2zrX7MMo5MBMGSyPvIIq2JyV+RTqQ8/8YBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}