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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4eb7fa72f92df7b971dc7f78f7b0dcca7e45f1d529652e4f21a75227cf488f' 
  AND token = 'nRiDHI8EqBHL0OLiazGAtDm9PQRc6nW3QMbANjzJimE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}