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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65f6a6811bae08268a48a02bca89d1b4c01e386f28d35f12ca698ab81244c63' 
  AND token = 'J7VVbUM5UDWMsLlgchK4hSLOg4AXyD/ua2jTw/nBX6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}