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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd4f51d393f1922b9dc52baa948e2acf95c485be262e9ee986bbbc164732776' 
  AND token = 'd6B6v8FOaSi8sRtNjURzdfgxzYlY49mwvO9tznnuAZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}