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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7561ce1c5009b47ea52b3ac7b87089097edc581a11d9c612702f8313021885' 
  AND token = 'gT1dm/lp0PlZTxzKx56AkuNlu9zvwCYqX2+fz9PIgmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}