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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43328b7f525cc05164ae0ff78931ab46bd8ef6c1920ec32d8080b69ba77887a' 
  AND token = '+MqYr28qABb8CTinmZajEOk0F5dL2Tjjfv1S0nfKyk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}