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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12d7eec9344e1d6db3c632728bf7b5cf53eb0a8fc44697a061262ae6db4fd70' 
  AND token = 'si2B9YaEgwRwjjgzcIn8CsLz1yiCCdZBeK6pZc3piB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}