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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ef170e5f5055f594d9625d9e6afe06722889caa5dc2fe7fe810b8c8d80aeabb' 
  AND token = 'vsVIIxHyjFEU/AiQzABae18iWNdCOTId6LPflag7pJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}