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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183d0d458b0b543e95f68d87db4d6de77e0ce891b1ef2d115dc74dc094282654' 
  AND token = '07y+Kn3dIgPyyOrRMzZlOTHC+9eLWQxX+C6c5JhI0TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}