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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1376d8782d23147a5e7835a1d3bd0763654a11cdb970fad10eddd13f3794b3ee' 
  AND token = 'FJQdeIdAcRZQCTWSQTST+W+GHQ2l2/dVNXZL8w79tps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}