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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cae27d6a1b20405c543784a0178b515e358528e0b12b44e800e18c2c12906e58' 
  AND token = 'sadUF6ZE2TqMbANlsP5ecsO02F88Y0dGGyZSeYH02AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}