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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2325fbb46f7182d4ef155b2d92464ab69e65af388349311a32be22099568f30' 
  AND token = 'bHXX2ufLEW6rFhpCThTTQNvqo/LFKXFs5Ug69yjmYaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}