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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416cbd20dd522c0b572a45f01ac9f1acaf285c68194057d3d06a34229826ae2c' 
  AND token = 'rRZuDjFWm3XSoN5W6l/2EFBpbmFmcsB4NfPvdRn1wVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}