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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c44bb9763766fa86868b232553b10eef73461c72dca15bf417f215da6c81e1' 
  AND token = 'G2gUv+L/Qfl5cBo2LpA3LseJuBXelIlBIUtDJuLqWlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}