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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ced03618a9a51f584e28ac86be20fd173cbd529ffdb207ae329cb437f2427365' 
  AND token = 'r0LZXPt2Pp0CXfgO8UbL9di/t9KYI4fRmZmrQ4FfXsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}