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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54db7f05e4b83e2cf5c867d0befa17c5f9fe799e3253cf90054e6544577db744' 
  AND token = 'lWiTf0kgEo4AtL/ZUFwVKd5thK8qxTx1rX4XAIHGHjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}