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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '148dadf1a352c502a600d79b0d16f42dbb19f58aaec78746d88298fa558ea4cb' 
  AND token = 'vmcgWvOlvvDCtGBHGBMW4cfChvw0TRfkR+7GrnHROXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}