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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186c6a73a20277a4e0433038b3290e5d39b3a96cfaafbb4a7d5e444e465bc2b2' 
  AND token = 'PWm19Ty/+WtY4Ni/dvzMqHaX4uN366BnAuUCxj2TGYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}