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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5f7de6849a2a1149059c24cfaf589c1cdc3b2226d93ac27a71a53ae4f9dbe3' 
  AND token = 'i5AjVPXteHgIL4cO9b9yxZZaeW/ODIKT994SbGtwrPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}