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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5ae0ca2e796e9a16caa53f07a53baa77cdf02020b957755e1f5018faefffce' 
  AND token = 'DNOGKb7OZRkUQDsYxjmGsqFEbeX+BorsHGBymCgy1o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}