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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387efeb39e7f97d4a1808f70d226d53b29a92d119c010152074bd538ede0599d' 
  AND token = 'jpuwkBMFWruw7ypat3rPmqUwTrwMhy2UQspSx42rjFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}