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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bfa782745f383d686df590711d8cf4a96f6b42abfa4187113e392f3fd50757' 
  AND token = 'xx07Z6SMBn708N7PMh3zLpk0Z7cF8mLCEoexDtAmSDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}