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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd32060abff35c78c7a2de4b2cf59e1be2295d31b289f71f1df2cdad0b3825b10' 
  AND token = 'hKdzrgEBT5C1MPFwB09dOe2ttBIvbVy1O4VXQQhr3l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}