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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5263d21a215a8b9047f38ee9b7697d6deb0d200c2289b782f74693399de73fd' 
  AND token = 'HQIEWc0aSoNDWGt6towgZjATHk/1e7sR2eaZk9TwnPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}