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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c187b04ca3ade1149dc4043aa35f13f1f913dae3cb995720de65c88e05be4c' 
  AND token = 'B/s1OChgBorOPZCHkEow1L3QT4mGyeNt8Z2Wgtd8+pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}