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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7b5009555c749851aeefd15e45001b89b5f5f3449b7ea8882e724338cd0d56' 
  AND token = '5SRxmMMpfn+b2xVSMAXHuH3Hb/+YGuugRv2xaKBkwjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}