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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11063c1a7e38341665b2dc428fa22e1203fcbab3cdc4a86a8e4061c4995496b3' 
  AND token = 'e6aOqhRIyeCRurwO0ZGcTJuPH0W5GKrRz5gTkCSwc2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}