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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf859d8553ff0bb289e00b5d2303d3b3446bae6513036037593f28b057b38fdc' 
  AND token = 'TCVrbd6rMcPLcNVE8VIfrCh6bgaClv6KyKq3YuSyyQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}