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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e11d245735a7a3e355912cf22c020b5534a124c3269a2e9b671538e6b6a2689' 
  AND token = 'JXj/zZBbc2xEUfcipB346D8YoAuBR+vaD3xHzS/mWUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}