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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b703bb0b6c1e1b6d17d712e90ceaeb3421d80f339f13e45434e06e33d41e65e0' 
  AND token = 'wVRW0OS0P3DyqmEI6LYCJNJaLc/6xRwilX3emGe3aSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}