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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15487b17002580123988cdfdceb1a41143e27c80704100d270d21480211d2d1' 
  AND token = 'W6p4zMhSefu5flfcn/Rw2M4rHKNC7ajfa4WcZ1txF9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}