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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea78a9bc2630a2dc4ac53a49e787a0aeae727b5733b19293cf99cf9c130f0a0c' 
  AND token = '79hwzjDwBaytv489b2r7Mz/4DyQrDHhpn3UGa2KOaLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}