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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9b8cfa9338d753cdeae50ea513b81977b6fe23c3177f2af1ea16a8af18ac68' 
  AND token = 'RXS8GIBjZ5l++mEGCYc2BYKnpDHqEqNVa3VkqUWcGMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}