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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e423d55644cf9f20c8391ffb5aff2ec6915bcd7e63c276640d9f478c3ee8da4' 
  AND token = 'L5Ja5O7Xhm/d65/Zexs/cX8RfEPd0nrdALRm82lPPHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}