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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6bb0326a0d69d7a6aba2bd764f91eb16fcf944014ca49399008109ea7d1b953' 
  AND token = 'NUi+P8r7GwREFfP3+MOtMKaBaLTP62XgkWGgBEe/gU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}