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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c41ecc3615daf4490b110520619bc2575c1384a1bb21f927d1fc2c0c0fa2b49' 
  AND token = '5ojHphgib6q3116gC5tqsQbddunN+oIR0twklyT9yAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}