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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a08dab5da6e4facebf980580fdc53efa045fb8cec3617951f048e2badc07ecf' 
  AND token = 'XDZS5JC6mQJgNK2lCJAw2Jz9sv3rtqDnaC8o1FqGR9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}