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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8e374c4e6c17b84ed7049e6369aae1769b4b6027be9fd50718d813cfd1bbb6' 
  AND token = 'Y6Zj/ndWdT36kdkkZEXm0FZXfx9uEjskLu2eqvOOazs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}