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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2020b68a30071d115186fd004ad0e9dffbc9c9b55ea4f1f040d65400e4ce8a' 
  AND token = 'dWnw3b0osWljeilJItJrmqyrTmzIGggPjftEozCTRaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}