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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578887ec45fa2c9d8d17b59f515d5eb61c7b5ef0270fa83d2288abc866e66a71' 
  AND token = 'XwabWY7pOyno4aG8gAKNchi4OMia5fl4DIQ4xx38AJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}